Father Karras was one of the priests who exorcises the demon from young Regan MacNeil. He is a Jesuit psychiatrist suffering a crisis of faith. Karras somewhat fits the literary concept of a "whiskey priest". Father Karras searches for proof to lead an exorcism, yet during his investigation he comes to realize that there is no better way for God to prove His own existence than to reveal the foul presence of Pazuzu. During the exorcism, Pazuzu frequently brings up the subject of Karras's mother's death and how he wasn't there to see her die, which seems to trouble Karras emotionally.
Father Karras dies by throwing himself down a flight of stone steps in order to purge the demon from his own body after having coaxed it out of Regan's.
In the sequel, Legion, it is revealed that after the demon departed, another evil spirit invaded Karras's body. Karras was found wandering and amnesiac and was placed in the care of a mental hospital near Washington DC. While incarcerated there, the spirit suppresses Karras's personality and makes forays into the bodies of other patients in order to commit a series of ritual murders.
Damien Karras was born on April 12, 1935 to a Greek family. He became a Jesuit priest on July 30, 1957. Over the years, the priest began to doubt the existence of God, the Devil, and many Biblical and supernatural beings. Still a Jesuit, he decided to become a psychiatrist.
On February 29, 1975, along with fellow-Jesuit Father Lankester Merrin, Karras attempts to exorcise 12-year-old Regan MacNeil (who was possessed by the demon Pazuzu). In the process, Merrin dies from exhaustion (probably a heart attack) and an embittered Karras attacks the possessed child, forcing the demon to channel itself into him instead. Karras, briefly dominated by the demon, throws himself out the window of the MacNeils' residence, seeing it as his chance to purge the world of Pazuzu; tumbling down the stairs of M Street to his death.
At the same time that Karras died, a criminal by the name of James Venamun (the infamous "Gemini Killer") was executed. Pazuzu left the body of the dead Karras and placed Venamun's soul into Karras's body as a means to revenge for having been thrown out of Regan MacNeil's. The body was interred. Soon, since there was still a soul in Karras, the body escaped his grave and he was found roaming the streets of Washington DC. Soon, he was placed under the care of a mental hospital. He remained in Cell 11 for 15 years.
His brain and bone tissues mended over time, but he alternated between his own personality and that of Venamun. Also, the spirit of Venamun left Karras's body by night to invade the other patients in the ward, making them commit murders for him without Venamun taking the blame. The Gemini Killer had come back to wreak havoc.
During a course of an exorcism, Venamun is forced to abandon Karras's body and Lt. William Kinderman shoots Karras several times, ending Karras's life for the final time.
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